Hepatic Dose : No dosage adjustments are recommended. Titrate to responseĭose in Patients undergoing Renal Replacement Therapies Renal Dose : Dose in Renal Impairment GFR (mL/min)ĭose as in normal renal function. Interaction :Ĭeftriaxone: Result in life-threatening damage to the lungs and kidneys.Īntibiotics: Decreases the absorption of antibiotics like quinolones.ĭigoxin: Increases the effects of digoxin and lead to irregular heartbeats.ĭiltiazem: Decreases the effectiveness of diltiazem. Metastatic calcifications, nephrocalcinosis, extravasation of IV calcium chloride or gluconate can cause tissue necrosis, hypercalcemia, hypophosphatemia, dry mouth, constipation, belching, stomach pain, vomiting, abdominal distension, flatulence.
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